Miss Caroline Price

Institute Administrator and PA to Profesor Bernard Keavney

Publications

2013

  • Anand, S. S., Meyre, D., Pare, G., Bailey, S. D., Xie, C., Zhang, X., ... Price, C. (2013). Genetic information and the prediction of incident type 2 diabetes in a high-risk multiethnic population: The EpiDREAM genetic study. Diabetes Care, 36(9), 2836-2842. DOI:10.2337/dc12-2553. Publication link: e357461a-b47e-489d-aeca-19cd9165e2a2 | PubMed:23603917
  • Bates, M. G. D., Hollingsworth, K. G., Newman, J. H., Jakovljevic, D. G., Blamire, A. M., MacGowan, G. A., ... Price, C. (2013). Concentric hypertrophic remodelling and subendocardial dysfunction in mitochondrial DNA point mutation carriers. European Heart Journal Cardiovascular Imaging, 14(7), 650-658. DOI:10.1093/ehjci/jes226. Publication link: 622e91ae-b95d-46d1-b6b6-6dcb8f0b3318 | PubMed:23129433
  • Cordell, H. J., Töpf, A., Mamasoula, C., Postma, A. V., Bentham, J., Zelenika, D., ... Price, C. (2013). Genome-wide association study identifies loci on 12q24 and 13q32 associated with Tetralogy of Fallot. Human Molecular Genetics, 22(7), 1473-1481. [dds552]. DOI:10.1093/hmg/dds552. Publication link: 9685d81f-80c1-4bd0-90fc-a3a28e88fbec | PubMed:23297363
  • Harper, A. R., Mayosi, B. M., Rodriguez, A., Rahman, T., Hall, D., Mamasoula, C., ... Price, C. (2013). Common Variation Neighbouring Micro-RNA 22 Is Associated with Increased Left Ventricular Mass. PLoS ONE, 8(1), [e55061]. DOI:10.1371/journal.pone.0055061. Publication link: fd12d482-af1a-469d-993d-479643f39df7 | PubMed:23372812
  • Price, C., Bates, M. G. D., Newman, J. H., Jakovljevic, D. G., Hollingsworth, K. G., Alston, C. L., ... Gorman, G. S. (2013). Defining cardiac adaptations and safety of endurance training in patients with m.3243A>G-related mitochondrial disease. International Journal of Cardiology, 168(4), 3599-3608. DOI:10.1016/j.ijcard.2013.05.062. Publication link: 8d531d2b-e6cc-46f7-b120-a6e754f77996 | PubMed:23742928
  • Price, C., Cordell, H. J., Bentham, J., Topf, A., Zelenika, D., Heath, S., ... Keavney, B. D. (2013). Genome-wide association study of multiple congenital heart disease phenotypes identifies a susceptibility locus for atrial septal defect at chromosome 4p16. Nature Genetics, 45(7), 822-824. DOI:10.1038/ng.2637. Publication link: 9da5b562-a017-498f-9325-f16f53a0ac7a | PubMed:23708191
  • Price, C., Lee, K., Santibanez-Koref, M., Polvikoski, T., Birchall, D., Mendelow, A. D., & Keavney, B. (2013). Increased expression of fatty acid binding protein 4 and leptin in resident macrophages characterises atherosclerotic plaque rupture. Atherosclerosis, 226(1), 74-81. DOI:10.1016/j.atherosclerosis.2012.09.037. Publication link: 45ea6a4b-e728-4240-94fb-295241d92ae8 | PubMed:23122912
  • Price, C., Palomino Doza, J., Topf, A., Bentham, J., Bhattacharya, S., Cosgrove, C., ... Keavney, B. (2013). Low-frequency intermediate penetrance variants in the ROCK1 gene predispose to Tetralogy of Fallotw. BMC genetics, 14, [57]. DOI:10.1186/1471-2156-14-57. Publication link: 54958deb-1cd4-4530-8f2b-483390a519cb | PubMed:23782575
  • Price, C., Vermeer, A. M. C., van Engelen, K., Postma, A. V., Baars, M. J. H., Christiaans, I., ... Keavney, B. (2013). Ebstein anomaly associated with left ventricular noncompaction: An autosomal dominant condition that can be caused by mutations in MYH7. American Journal of Medical Genetics - Seminars in Medical Genetics, 163(3), 178-184. DOI:10.1002/ajmg.c.31365. Publication link: 986a4ad4-15c3-44af-b377-e1cc00f3c8e8 | PubMed:23794396
  • van Engelen, K., Postma, A. V., van de Meerakker, J. B. A., Roos-Hesselink, J. W., Helderman-Van den Enden, A. T. J. M., Vliegen, H. W., ... Price, C. (2013). Ebstein's anomaly may be caused by mutations in the sarcomere protein gene MYH7. Netherlands Heart Journal, 21(3), 113-117. DOI:10.1007/s12471-011-0141-1. Publication link: ebafd03d-8122-4c94-a30a-7f1f9935b3f2 | PubMed:21604106

2012

  • Price, C., Chen, C. M., Bentham, J., Cosgrove, C., Braganca, J., Cuenda, A., ... Bhattacharya, S. (2012). Functional Significance of SRJ Domain Mutations in CITED2. PLoS ONE, 7(10), [e46256]. DOI:10.1371/journal.pone.0046256. Publication link: 20882fee-b59c-45ee-a2a8-a4f13b1679b8 | PubMed:23082118
  • Price, C., Goodship, J. A., Hall, D., Topf, A., Mamasoula, C., Griffin, H., ... Keavney, B. (2012). A common variant in the PTPN11 gene contributes to the risk of tetralogy of fallot. Circulation: Cardiovascular Genetics, 5(3), 287-292. DOI:10.1161/CIRCGENETICS.111.962035. Publication link: 2316bd33-fd05-40b8-8086-c08585832148 | PubMed:22503907
  • Price, C., Helgadottir, A., Gretarsdottir, S., Thorleifsson, G., Holm, H., Patel, R. S., ... Stefansson, K. (2012). Apolipoprotein(a) genetic sequence variants associated with systemic atherosclerosis and coronary atherosclerotic burden but not with venous thromboembolism. Journal of the American College of Cardiology, 60(8), 722-729. DOI:10.1016/j.jacc.2012.01.078. Publication link: ef7dfe30-6800-4d59-985a-5335c56cc611 | PubMed:22898070
  • Price, C., Hoffmann, J., Fiser, K., Weaver, J., Dimmick, I., Loeher, M., ... Spyridopoulos, I. (2012). High-Throughput 13-Parameter Immunophenotyping Identifies Shifts in the Circulating T-Cell Compartment Following Reperfusion in Patients with Acute Myocardial Infarction. PLoS ONE, 7(10), [e47155]. DOI:10.1371/journal.pone.0047155. Publication link: fda5153b-d0ee-4749-b61e-72924d717c5a | PubMed:23077561
  • Price, C., Hollingsworth, K. G., Blamire, A. M., Keavney, B. D., & MacGowan, G. A. (2012). Left ventricular torsion, energetics, and diastolic function in normal human aging. American Journal of Physiology - Heart and Circulatory Physiology, 302(4), H885-H892. DOI:10.1152/ajpheart.00985.2011. Publication link: 2dd4b492-5e7e-466a-b060-2059fd33bfa7 | PubMed:22180656
  • Price, C., Horvath, R., Holinski-Feder, E., Neeve, V. C. M., Pyle, A., Griffin, H., ... Chinnery, P. F. (2012). A new phenotype of brain iron accumulation with dystonia, optic atrophy, and peripheral neuropathy. Movement Disorders, 27(6), 789-793. DOI:10.1002/mds.24980. Publication link: 54252309-935f-46e3-a7c0-7bc4f3e2c7c0 | PubMed:22508347
  • Price, C., Soemedi, R., Topf, A., Wilson, I. J., Darlay, R., Rahman, T., ... Keavney, B. D. (2012). Phenotype-specific effect of chromosome 1q21.1 rearrangements and GJA5 duplications in 2436 congenital heart disease patients and 6760 controls. Human Molecular Genetics, 21(7), 1513-1520. [ddr589]. DOI:10.1093/hmg/ddr589. Publication link: 262ec424-5155-4c45-848b-714fc37c74f7 | PubMed:22199024
  • Price, C., Soemedi, R., Wilson, I. J., Bentham, J., Darlay, R., Töpf, A., ... Keavney, B. D. (2012). Contribution of global rare copy-number variants to the risk of sporadic congenital heart disease. American Journal of Human Genetics, 91(3), 489-501. DOI:10.1016/j.ajhg.2012.08.003. Publication link: 07443cd5-189c-4d83-b486-75ea4bd7d170 | PubMed:22939634
  • Price, C., Twigg, S. R. F., Lloyd, D., Jenkins, D., Elçioglu, N. E., Cooper, C. D. O., ... Wilkie, A. O. M. (2012). Mutations in multidomain protein MEGF8 identify a carpenter syndrome subtype associated with defective lateralization. American Journal of Human Genetics, 91(5), 897-905. DOI:10.1016/j.ajhg.2012.08.027. Publication link: d8c33eee-5fe2-4c2b-a30e-5c96e5cd0b45 | PubMed:23063620
  • Price, C., Yousaf, F., Collerton, J., Kingston, A., Kenny, A., Davies, K., ... Keavney, B. (2012). Prevalence of left ventricular dysfunction in a UK community sample of very old people: The Newcastle 85+ study. Heart, 98(19), 1418-1423. DOI:10.1136/heartjnl-2012-302457. Publication link: 6b2a9b0a-2d72-4940-ad96-1ececf06b391 | PubMed:22859497
  • Tan, H. L., Glen, E., Töpf, A., Hall, D., O'Sullivan, J. J., Sneddon, L., ... Price, C. (2012). Nonsynonymous variants in the SMAD6 gene predispose to congenital cardiovascular malformation. Human Mutation, 33(4), 720-727. DOI:10.1002/humu.22030. Publication link: 38725c41-0f1e-4f3a-a104-8709925daf55 | PubMed:22275001

2011

2010

  • Bailey, S. D., Xie, C., Do, R., Montpetit, A., Diaz, R., Mohan, V., ... Price, C. (2010). Variation at the NFATC2 locus increases the risk of thiazolidinedione- induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study. Diabetes Care, 33(10), 2250-2253. DOI:10.2337/dc10-0452. Publication link: dc48e5d3-0499-4a75-8067-fc9579ac6ac2 | PubMed:20628086
  • Keavney, B., & Price, C. (2010). The interleukin-1 cluster, dyslipidaemia and risk of myocardial infarction. BMC Medicine, 8, [6]. DOI:10.1186/1741-7015-8-6. Publication link: 112725e9-36e2-4e48-adf6-6bd5f5f83263 | PubMed:20070881
  • Price, C., Cunnington, M. S., Koref, M. S., Mayosi, B. M., Burn, J., & Keavney, B. (2010). Chromosome 9p21 SNPs associated with multiple disease phenotypes correlate with ANRIL expression. PLoS Genetics, 6(4). DOI:10.1371/journal.pgen.1000899. Publication link: 45840d10-51d4-4895-af3f-2fb7d0f41b26 | PubMed:20386740
  • Price, C., Griffin, H. R., Töpf, A., Glen, E., Zweier, C., Stuart, A. G., ... Goodship, J. A. (2010). Systematic survey of variants in TBX1 in non-syndromic tetralogy of Fallot identifies a novel 57 base pair deletion that reduces transcriptional activity but finds no evidence for association with common variants. Heart, 96(20), 1651-1655. DOI:10.1136/hrt.2010.200121. Publication link: b4805d39-f777-4a55-b7c2-caa973590c30 | PubMed:20937753
  • Price, C., Kiechl, S., Laxton, R. C., Xiao, Q., Hernesniemi, J. A., Raitakari, O. T., ... Ye, S. (2010). Coronary artery disease-related genetic variant on chromosome 10q11 is associated with carotid intima-media thickness and atherosclerosis. Arteriosclerosis, Thrombosis, and Vascular Biology, 30(12), 2678-2683. DOI:10.1161/ATVBAHA.110.213785. Publication link: 2603ffe6-3050-42c4-b317-142295d89afa | PubMed:20847302
  • Price, C., Lang, C. C., Gupta, S., Kalra, P., Keavney, B., Menown, I., ... Padmanabhan, S. (2010). Elevated heart rate and cardiovascular outcomes in patients with coronary artery disease: Clinical evidence and pathophysiological mechanisms. Atherosclerosis, 212(1), 1-8. DOI:10.1016/j.atherosclerosis.2010.01.029. Publication link: 004dc6e9-e063-4635-8237-5171938f50b9 | PubMed:20152981
  • Price, C., Van Engelen, K., Topf, A., Keavney, B. D., Goodship, J. A., Van Der Velde, E. T., ... Mulder, B. J. M. (2010). 22q11.2 Deletion syndrome is under-recognised in adult patients with tetralogy of fallot and pulmonary atresia. Heart, 96(8), 621-624. DOI:10.1136/hrt.2009.182642. Publication link: ef4bf6f6-76f2-4c76-a6da-ff76fa53d0c5 | PubMed:20357389

2009

  • Anand, S. S., Xie, C., Paré, G., Montpetit, A., Rangarajan, S., McQueen, M. J., ... Price, C. (2009). Genetic variants associated with myocardial infarction risk factors in over 8000 individuals from five ethnic groups the INTERHEART genetics study. Circulation: Cardiovascular Genetics, 2(1), 16-25. DOI:10.1161/CIRCGENETICS.108.813709. Publication link: d6465405-513d-47aa-97fa-1f1fc37e15eb | PubMed:20031563
  • Cunnington, M. S., Kay, C., Avery, P. J., Mayosi, B. M., Koref, M. S., Keavney, B., & Price, C. (2009). STK39 polymorphisms and blood pressure: an association study in British Caucasians and assessment of cis-acting influences on gene expression.BMC medical genetics, 10, 135. DOI:10.1186/1471-2350-10-135. Publication link: 82495f7e-624d-4ea5-8696-e99562140ead | PubMed:20003416
  • Keavney, B., Monaco, A. D., Bruno, I., Sestito, A., Lamendola, P., Barone, L., ... Price, C. (2009). Cardiac adrenergic nerve function and microvascular dysfunction in patients with cardiac syndrome X. Heart, 95(7), 550-554. DOI:10.1136/hrt.2008.146662. Publication link: 5aae4644-5bd0-48b1-a802-70dc5fcd7189 | PubMed:18977801
  • Leong, F. T., Freeman, L. J., Keavney, B. D., & Price, C. (2009). Fresh fields and pathways new: Recent genetic insights into cardiac malformation. Heart, 95(6), 442-447. DOI:10.1136/hrt.2006.105130. Publication link: da3bd57b-ab09-465a-a921-16730277b7ab | PubMed:19252006
  • Price, C., Alvarez-Madrazo, S., Padmanabhan, S., Mayosi, B. M., Watkins, H., Avery, P., ... Connell, J. M. (2009). Familial and phenotypic associations of the aldosterone renin ratio. Journal of Clinical Endocrinology and Metabolism, 94(11), 4324-4333. DOI:10.1210/jc.2009-1406. Publication link: c17317f8-7d22-4cd0-a7ae-a298a0800af2 | PubMed:19820005
  • Price, C., Griffin, H. R., Hall, D. H., Topf, A., Eden, J., Stuart, A. G., ... Keavney, B. (2009). Genetic variation in VEGF does not contribute significantly to the risk of congenital cardiovascular malformation. PLoS ONE, 4(3), [e4978]. DOI:10.1371/journal.pone.0004978. Publication link: 2ae6ed1c-0929-415c-bbae-d5685aa8c750 | PubMed:19308252
  • Price, C., Thomas, H. E., Parry, G., Dark, J. H., Arthur, H. M., & Keavney, B. D. (2009). Circulating endothelial progenitor cell numbers are not associated with donor organ age or allograft vasculopathy in cardiac transplant recipients. Atherosclerosis, 202(2), 612-616. DOI:10.1016/j.atherosclerosis.2008.05.020. Publication link: bf8ae351-44f6-4fee-926b-8eadc6b038ee | PubMed:18589426

2008